Harrison W O, Sanchez P L, Lancaster D J, Kerbs S B, Berg S W
Sex Transm Dis. 1984 Jan-Mar;11(1):30-1. doi: 10.1097/00007435-198401000-00007.
Fifty-five men with culture-proved gonococcal urethritis caused by either penicillin-sensitive or penicillinase-producing Neisseria gonorrhoeae were treated with 1 g of ceftizoxime given intramuscularly. All patients were cured, including 26 (47%) with penicillinase-producing strains. Patients experienced no local or systemic side effects and tolerated the injection of ceftizoxime well. These results show that ceftizoxime is an effective alternative to either spectinomycin or cefoxitin in treatment of uncomplicated gonococcal urethritis caused by penicillin-resistant bacteria.
55名经培养证实患有由青霉素敏感或产青霉素酶的淋病奈瑟菌引起的淋菌性尿道炎的男性，接受了1克头孢唑肟肌肉注射治疗。所有患者均治愈，其中包括26名（47%）感染产青霉素酶菌株的患者。患者未出现局部或全身副作用，对头孢唑肟注射耐受性良好。这些结果表明，在治疗由耐青霉素细菌引起的单纯性淋菌性尿道炎方面，头孢唑肟是大观霉素或头孢西丁的有效替代药物。
