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单次1克剂量头孢噻肟治疗产青霉素酶淋病奈瑟菌引起的感染。

Single 1 g dose of cefotaxime in the treatment of infections due to penicillinase-producing strains of Neisseria gonorrhoeae.

作者信息

de Koning G A, Tio D, van den Hoek J A, van Klingeren B

出版信息

Br J Vener Dis. 1983 Apr;59(2):100-2. doi: 10.1136/sti.59.2.100.

Abstract

One hundred and two patients with an uncomplicated infection due to penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) were treated with a single 1 g dose of cefotaxime. At follow-up within 15 days all genital and rectal infections were cured. Pharyngeal infections also seemed to respond to this treatment. A relatively high proportion (30.9%) of patients, however, developed post-gonococcal urethritis.

摘要

102例因产青霉素酶淋病奈瑟菌(PPNG)引起单纯感染的患者接受了单次1g剂量头孢噻肟的治疗。在15天内的随访中,所有生殖器和直肠感染均得到治愈。咽部感染似乎也对这种治疗有反应。然而,相当高比例(30.9%)的患者发生了淋菌性尿道炎后尿道炎。

相似文献

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Single-dose treatment of uncomplicated gonorrhea in men with intramuscular and oral thiamphenicol.
Sex Transm Dis. 1984 Oct-Dec;11(4 Suppl):404-6. doi: 10.1097/00007435-198410001-00023.

本文引用的文献

3
Treatment of uncomplicated gonorrhea with cefotaxime.用头孢噻肟治疗单纯性淋病。
Sex Transm Dis. 1981 Jul-Sep;8(3):187-91. doi: 10.1097/00007435-198107000-00003.
7
Biochemical and genetical approaches to the mechanism of action of penicillin.青霉素作用机制的生化与遗传学研究方法。
Philos Trans R Soc Lond B Biol Sci. 1980 May 16;289(1036):273-83. doi: 10.1098/rstb.1980.0045.
8
Pharmacokinetics of cefotaxime.头孢噻肟的药代动力学。
Antimicrob Agents Chemother. 1979 Nov;16(5):592-7. doi: 10.1128/AAC.16.5.592.

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