Luzzi I, Caprioli A, Falbo V, Guarino A, Capano G, Alessio M, Malamisura B, Gianfrilli P
J Med Microbiol. 1986 Aug;22(1):29-31. doi: 10.1099/00222615-22-1-29.
A cell-culture assay was used to detect toxins directly in stools from sporadic cases of infantile diarrhoea. Cytotoxins were revealed in 11 out of 58 samples from children with diarrhoea, nine of whom had no common enteric pathogens in their stools. A preliminary characterisation of the cytotoxins was obtained by neutralisation tests with clostridial antitoxins.
采用细胞培养试验直接检测散发性婴儿腹泻病例粪便中的毒素。在58例腹泻儿童的样本中,有11例检测出细胞毒素,其中9例粪便中无常见肠道病原体。通过用梭菌抗毒素进行中和试验,对细胞毒素进行了初步鉴定。