第三代头孢菌素在人体血液中的活性。
Activity of third-generation cephalosporins in human blood.
作者信息
Shah P M, Jaenisch E
出版信息
Clin Ther. 1983;6(1):72-8.
PMID:6325006
Abstract
Activity of cefotaxime, ceftriaxone, cefotetan, and latamoxef against Escherichia coli was evaluated in whole human blood. At subinhibitory levels no effect was seen. At concentrations at or exceeding the MIC, cefotaxime was rapidly bactericidal, and latamoxef was the second most active compound. With ceftriaxone and cefotetan, the organism grew better in blood containing the antibiotic than in blood alone.
摘要
在全血中评估了头孢噻肟、头孢曲松、头孢替坦和拉氧头孢对大肠杆菌的活性。在亚抑菌水平下未观察到效果。在等于或超过最低抑菌浓度（MIC）的浓度下，头孢噻肟具有快速杀菌作用，拉氧头孢是第二活性最强的化合物。对于头孢曲松和头孢替坦，该生物体在含有抗生素的血液中比在单独的血液中生长得更好。
相似文献
1
Activity of third-generation cephalosporins in human blood.第三代头孢菌素在人体血液中的活性。
Clin Ther. 1983;6(1):72-8.
2
[Comparative study of ceftriaxone, cefotaxime and moxalactam against 150 Gram negative strains (author's transl)].头孢曲松、头孢噻肟和拉氧头孢对150株革兰氏阴性菌的比较研究（作者译）
Pathol Biol (Paris). 1982 Jun;30(6):341-4.
3
[Comparison of antimicrobial activity and stability to beta-lactamases of cefoperazone, cefotaxime, lamoxactam and ceftriaxon].头孢哌酮、头孢噻肟、拉氧头孢及头孢曲松的抗菌活性及对β-内酰胺酶稳定性的比较
Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1982 Jun;252(2):208-21.
4
In-vitro and in-vivo efficacy of ceftriaxone, moxalactam, and chloramphenicol against Haemophilus influenzae type b.
J Antimicrob Chemother. 1982 Dec;10(6):517-25. doi: 10.1093/jac/10.6.517.
5
6
Antimicrobial activity, beta-lactamase stability and beta-lactamase inhibition of cefotetan and other 7-alpha-methoxy beta-lactam antimicrobials.头孢替坦及其他7-α-甲氧基β-内酰胺类抗菌药物的抗菌活性、β-内酰胺酶稳定性及β-内酰胺酶抑制作用
Diagn Microbiol Infect Dis. 1983 Mar;1(1):71-83. doi: 10.1016/0732-8893(83)90035-4.
7
8
The serum bactericidal activity of latamoxef (moxalactam), cefoperazone and cefotaxime.拉氧头孢（羟羧氧酰胺菌素）、头孢哌酮和头孢噻肟的血清杀菌活性。
J Antimicrob Chemother. 1984 Nov;14(5):491-7. doi: 10.1093/jac/14.5.491.
9
10
Serum bactericidal activity of moxalactam and cefotaxime with and without tobramycin against Pseudomonas aeruginosa and Staphylococcus aureus.氨曲南及头孢噻肟单用或联用妥布霉素对铜绿假单胞菌和金黄色葡萄球菌的血清杀菌活性
Antimicrob Agents Chemother. 1981 Oct;20(4):539-41. doi: 10.1128/AAC.20.4.539.
Zotero 插件