Saitoh H, Yamada K, Goto Y, Kobayashi M, Horigome K, Nakano N, Sakai H, Kitamura H, Satoh H, Saitoh F
Jpn J Antibiot. 1983 Oct;36(10):2901-12.
Fifty-eight patients were treated with cefotaxime (CTX, Claforan) intravenously. Almost all patients (54 patients) had underlying diseases that were 16 cases of diabetes mellitus, 10 cases of respiratory diseases, 8 cases of cerebral vascular disturbance, 6 cases of renal diseases and blood diseases, 5 cases of carcinoma and hypertension, 4 cases of cholelithiasis, 3 cases of heart diseases and 7 cases of other diseases. The clinical efficacy of CTX in 34 cases of RTI, 11 cases of UTI, 8 cases of BTI and 5 cases of other infection was excellent in 11 cases, good in 27 cases, fair in 12 cases, poor in 4 cases and unclear in 4 cases. The over all clinical effectiveness was 70.4%. No adverse reaction was observed except for 2 cases (general fatigue in 1 case and eruption and itching in another). These results obtained should support the usefulness of CTX.
58例患者接受了静脉注射头孢噻肟（CTX，凯福隆）治疗。几乎所有患者（54例）都有基础疾病，其中糖尿病16例、呼吸系统疾病10例、脑血管疾病8例、肾脏疾病和血液疾病6例、癌症和高血压5例、胆结石4例、心脏病3例以及其他疾病7例。CTX治疗34例呼吸道感染（RTI）、11例尿路感染（UTI）、8例血流感染（BTI）和5例其他感染，临床疗效为优11例、良27例、中12例、差4例、不明确4例。总体临床有效率为70.4%。除2例（1例全身乏力，另1例皮疹伴瘙痒）外，未观察到不良反应。这些结果应支持CTX的有效性。
