Johnson A E, Nock B, Ryer H, Feder H
Neuroendocrinology. 1984 Mar;38(3):243-7. doi: 10.1159/000123898.
alpha 1-Receptors were measured in intact male guinea pigs during the course of postnatal development. Receptor concentrations were significantly higher at day 1 in hypothalamus and at days 1 and 14 in preoptic area than at day 60. Conversely, in cerebral cortex, receptor concentrations were significantly lower in neonatal animals than in 60-day-old animals. There was no change in affinity of the receptor during development. Castration has no apparent effect on alpha 1-receptor concentration in any brain area.
在新生雄性豚鼠出生后的发育过程中，对α1受体进行了测量。在下丘脑中，出生第1天的受体浓度显著高于出生第60天；在视前区，出生第1天和第14天的受体浓度显著高于出生第60天。相反，在大脑皮层中，新生动物的受体浓度显著低于60日龄动物。在发育过程中，受体的亲和力没有变化。去势对任何脑区的α1受体浓度均无明显影响。
