Fujii S I, Nakazono N, Sawada H, Ishii K, Kato M, Aoki K, Ohtsuka H, Fujinaga K
Jpn J Med Sci Biol. 1983 Dec;36(6):307-13. doi: 10.7883/yoken1952.36.307.
We studied the restriction endonuclease cleavage patterns of DNAs of adenovirus type 8 (Ad 8) isolated from epidemic keratoconjunctivitis cases. DNAs of 25 Ad 8 isolates collected during the period from 1975 to 1981 in Sapporo were subjected to enzymatic cleavage with PstI, BamHl , HindIII and SalI. On the basis of the cleavage patterns, the isolates were divided into two subtypes, A and B, both different from Trim strain used as the Ad 8 prototype strain. Subtype A was prevalent in the period from 1975 to 1978, while subtype B in the period from 1976 to 1981.
我们研究了从流行性角结膜炎病例中分离出的8型腺病毒（Ad 8）DNA的限制性内切酶切割模式。对1975年至1981年期间在札幌收集的25株Ad 8分离株的DNA用PstI、BamHl、HindIII和SalI进行酶切。根据切割模式，这些分离株被分为A和B两个亚型，均不同于用作Ad 8原型株的Trim株。A亚型在1975年至1978年期间流行，而B亚型在1976年至1981年期间流行。
