Takeuchi R, Nomura Y, Kojima M, Uchio E, Kobayashi N, Matumoto M
Division of Microbiology, Yokohama City Institute of Health, Kanagawa.
Microbiol Immunol. 1990;34(9):749-54. doi: 10.1111/j.1348-0421.1990.tb01052.x.
An outbreak of epidemic keratoconjunctivitis occurred at the department of ophthalmology of a hospital in Yokohama, involving 14 inpatients, 12 outpatients, and 2 doctors. Adenovirus type 37 (Ad-37) was isolated from the conjunctival swab in 12 of 18 cases. In neutralization tests, the isolates showed some cross-reaction with adenovirus type 19 (Ad-19). The Ad-37 isolates were indistinguishable from each other and from the prototype Ad-37, but distinct from the prototype Ad-19 in the restriction endonuclease analysis of viral DNA.
横滨一家医院的眼科发生了一起流行性角结膜炎疫情，涉及14名住院患者、12名门诊患者和2名医生。在18例病例中的12例结膜拭子中分离出37型腺病毒（Ad-37）。在中和试验中，分离株与19型腺病毒（Ad-19）表现出一些交叉反应。Ad-37分离株彼此之间以及与原型Ad-37无法区分，但在病毒DNA的限制性内切酶分析中与原型Ad-19不同。
