蛛网膜下腔出血患者血浆肾上腺素和去甲肾上腺素浓度的临床意义
Clinical significance of plasma adrenaline and noradrenaline concentrations in patients with subarachnoid haemorrhage.
作者信息
Benedict C R, Loach A B
出版信息
J Neurol Neurosurg Psychiatry. 1978 Feb;41(2):113-7. doi: 10.1136/jnnp.41.2.113.
Abstract
Plasma adrenaline and noradrenaline concentrations were measured in 21 patients after subarachnoid haemorrhage and in 13 control patients. Plasma noradrenaline concentrations were significantly raised in patients recovering from subarachnoid haemorrhage, confirming clinical evidence of overactivity of the sympathetic nervous system. Plasma noradrenaline concentrations in patients with a poor result were significantly higher at the time of admission than in patients with a good result, and the differences became more significant two to three days later. Therefore, the measurement of plasma noradrenaline concentrations may be a valuable test to assist clinical assessment in distinguishing between the two groups preoperatively.
摘要
对21例蛛网膜下腔出血患者和13例对照患者测定了血浆肾上腺素和去甲肾上腺素浓度。蛛网膜下腔出血康复患者的血浆去甲肾上腺素浓度显著升高，证实了交感神经系统活动过度的临床证据。预后较差的患者入院时血浆去甲肾上腺素浓度显著高于预后良好的患者，且在两到三天后差异变得更加显著。因此，测定血浆去甲肾上腺素浓度可能是一项有价值的检查，有助于术前临床评估以区分这两组患者。
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