Kotchmar G S, Grose C, Brunell P A
Pediatr Infect Dis. 1984 Mar-Apr;3(2):142-5. doi: 10.1097/00006454-198403000-00015.
Chickenpox in the pregnant woman occasionally leads to infection and teratogenesis of the early to midgestational embryo. We describe the developmental assessment and clinical management of a 5-year-old girl with classic varicella congenital defects syndrome. This patient is unique with respect to (1) a generally favorable outcome in spite of the severity of her anomalies involving the eyes, limbs and skin, (2) a completely normal evaluation of her immunologic status and (3) a serologically documented herpes zoster infection at age 41 months.
孕妇感染水痘偶尔会导致孕早期至中期胚胎感染和致畸。我们描述了一名患有典型先天性水痘缺陷综合征的5岁女孩的发育评估和临床管理情况。该患者具有以下独特之处：（1）尽管其眼部、四肢和皮肤存在严重异常，但总体预后良好；（2）免疫状态评估完全正常；（3）血清学记录显示其在41个月大时感染过带状疱疹。
