Streissguth A P, Herman C S, Smith D W
J Pediatr. 1978 Mar;92(3):363-7. doi: 10.1016/s0022-3476(78)80420-x.
In a sample of 20 patients with the fetal alcohol syndrome, ages 9 months to 21 years, the average IQ was 65, with a range of 16 to 105; 60% of the patients had IQ's more than two standard deviations below the mean. The sample included patients who ranged in severity of dysmorphogenesis from mild to severe. The severity of the dysmorphic features was related to degree of mental deficiency; children with the most severe manifestations of FAS had an average IQ of 55, whereas children with lesser manifestations had an average IQ of 82. All children were growth deficient for height and/or head circumference, but in this study only height was significantly correlated with IQ. Environmental and behavioral characteristics of the sample are discussed, and two adults with the fetal alcohol syndrome are presented.
在一个由20名患有胎儿酒精综合征的患者组成的样本中，年龄从9个月到21岁不等，平均智商为65，范围在16至105之间；60%的患者智商比平均值低两个标准差以上。该样本包括畸形发生严重程度从轻度到重度不等的患者。畸形特征的严重程度与智力缺陷程度相关；胎儿酒精综合征表现最严重的儿童平均智商为55，而表现较轻的儿童平均智商为82。所有儿童身高和/或头围生长不足，但在本研究中只有身高与智商显著相关。讨论了样本的环境和行为特征，并介绍了两名患有胎儿酒精综合征的成年人。
