Friedman H M, Lewis M R, Nemerofsky D M, Plotkin S A
Pediatr Infect Dis. 1984 May-Jun;3(3):233-5. doi: 10.1097/00006454-198405000-00010.
Of 842 female employees at a pediatric hospital who were tested for cytomegalovirus antibody, 487 (57.8%) were seronegative. We also studied 228 females who had been employed for 3 or more months, and 139 (61.0%) were seronegative. One year after the initial serum 173 seronegative women provided a second sample. Eleven (6.4%) had seroconverted to cytomegalovirus, and none gave a history of significant illness in the interval. Of the 173 women 138 had patient contact jobs and 35 had noncontact jobs. In the contact group 10 of 138 (7.2%) seroconverted including 5 of 46 (10.9%) intensive care nurses, 2 of 11 (18.2%) women on the blood drawing or intravenous insertion team and 3 of 81 (3.7%) nurses on medical and surgical wards. In the noncontact group 1 of 35 (2.9%) seroconverted. Among female employees at a pediatric hospital the risk of cytomegalovirus is substantial and appears to be related to the type of patient contact.
在一家儿科医院接受巨细胞病毒抗体检测的842名女性员工中，487名（57.8%）血清学检测呈阴性。我们还研究了228名工作3个月或更长时间的女性，其中139名（61.0%）血清学检测呈阴性。在初次采血一年后，173名血清学阴性的女性提供了第二份样本。11名（6.4%）已血清转化为巨细胞病毒阳性，且在此期间均无重大疾病史。在这173名女性中，138名从事与患者接触的工作，35名从事非接触性工作。在接触组中，138名中有10名（7.2%）血清转化，其中包括46名重症监护护士中的5名（10.9%）、采血或静脉穿刺团队的11名女性中的2名（18.2%）以及内科和外科病房的81名护士中的3名（3.7%）。在非接触组中，35名中有1名（2.9%）血清转化。在儿科医院的女性员工中，感染巨细胞病毒的风险很大，而且似乎与接触患者的类型有关。
