Bosi A, Borsotti M, Ghelli P, Tozzi P, Bellesi G, Rossi Ferrini P
Acta Haematol. 1984;71(5):329-33. doi: 10.1159/000206610.
Serum angiotensin-I-converting enzyme (S-ACE) is elevated in active sarcoidosis. In Hodgkin's disease (HD) there are few reports with different and contrasting results. We studied S-ACE in 23 healthy controls and in 18 untreated and unsplenectomized patients with HD. In the same cases we studied also serum lysozyme. Lysozyme concentration was significantly higher in HD patients compared with normal controls (p less than 0.01) and was independent of stage, systemic symptoms and presence of mediastinal involvement. S-ACE activity in HD patients was lower than in healthy controls, but not significantly. The correlation coefficient between the two enzymes showed that there was no significant correlation both in controls and in patients.
血清血管紧张素转换酶（S-ACE）在结节病活动期升高。在霍奇金病（HD）中，相关报道较少，且结果各异、相互矛盾。我们对23名健康对照者以及18名未经治疗且未行脾切除术的HD患者进行了S-ACE研究。对这些患者我们还同时研究了血清溶菌酶。HD患者的溶菌酶浓度显著高于正常对照者（p<0.01），且与分期、全身症状及纵隔受累情况无关。HD患者的S-ACE活性低于健康对照者，但差异无统计学意义。两种酶之间的相关系数表明，对照者和患者中均无显著相关性。
