Alberts C, van der Schoot J B, van Daatselaar J J, Braat M C, Roos C M
Eur J Respir Dis. 1983 Jan;64(1):38-46.
67Ga scintigraphy, using a 67Ga accumulation score, was compared with serum lysozyme (LZM) and angiotensin-converting enzyme (ACE) levels in 34 patients with biopsy-proven, pulmonary sarcoidosis. Serum LZM and ACE values varied between 1.0 to 21.3 mg/l (mean 4.3 +/- 3.4 mg/l) and 33 to 146 U/l (mean 69 +/- 26 U/l), respectively. Normal values were found in 26 and 35% of the patients. All patients, however, had abnormal 67Ga uptake in the pulmonary hilar lymph nodes and/or parenchyma. The follow-up of untreated and treated patients supports the suggestion that 67Ga scintigraphy is more useful for assessing the extent and activity of the intrathoracic sarcoid lesions. Serum LZM and ACE measurements are helpful, but normal LZM and ACE values do not exclude activity and progression of disease in pulmonary sarcoidosis.
对34例经活检证实为肺结节病的患者，采用67镓积聚评分的67镓闪烁扫描法与血清溶菌酶（LZM）及血管紧张素转换酶（ACE）水平进行了比较。血清LZM和ACE值分别在1.0至21.3毫克/升（平均4.3±3.4毫克/升）和33至146国际单位/升（平均69±26国际单位/升）之间变化。分别有26%和35%的患者这些指标值正常。然而，所有患者肺门淋巴结和/或实质均有异常的67镓摄取。对未治疗和已治疗患者的随访支持了这样的观点，即67镓闪烁扫描法在评估胸内结节病病变的范围和活动度方面更有用。血清LZM和ACE检测有帮助，但LZM和ACE值正常并不能排除肺结节病患者疾病的活动和进展。
