Grönhagen-Riska C, Kurppa K, Fyhrquist F, Selroos O
Scand J Respir Dis. 1978 Aug;59(4):228-31.
Serum angiotensin-converting enzyme (ACE) activity and lysozyme (LZM) concentration in 22 silicosis and 18 asbestosis patients were studied. These patients were compared with 57 untreated and 36 treated sarcoidosis patients. In all groups significantly raised ACE and LZM mean values were noted. Untreated sarcoidosis patients had the highest values. Raised ACE activity in silicosis and asbestosis has not been reported before, and weakens the differential diagnostic value of this enzyme determination for sarcoidosis. The similar patterns of increased ACE and LZM mean values in all three diseases suggest that these enzymes have a common source.
对22例矽肺患者和18例石棉肺患者的血清血管紧张素转换酶（ACE）活性及溶菌酶（LZM）浓度进行了研究。将这些患者与57例未经治疗及36例经治疗的结节病患者进行了比较。在所有组中均观察到ACE和LZM的平均值显著升高。未经治疗的结节病患者的值最高。矽肺和石棉肺中ACE活性升高此前未见报道，这削弱了该酶测定对结节病的鉴别诊断价值。三种疾病中ACE和LZM平均值升高的相似模式表明这些酶有共同来源。
