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肺小细胞间变性癌。奥胡斯的经验(1976 - 1981年)

Small cell anaplastic carcinoma of the lung. The Aarhus experience 1976-1981.

作者信息

Schultz H P, Overgaard M, Steenholdt S, Sell A, Bentzen S M

出版信息

Acta Radiol Oncol. 1984;23(2-3):153-8. doi: 10.3109/02841868409136004.

DOI:10.3109/02841868409136004
PMID:6331084
Abstract

Over a 6-year period 179 patients with small cell carcinoma of the lung (SCLC), 152 with limited disease, 25 with extensive disease, and 2 who were not staged, were treated with chest irradiation and combination chemotherapy with CCNU, adriamycin and vinblastine. For all patients the 2-year survival was 19.9 +/- 3 per cent, and the 5-year survival 11.9 +/- 3 per cent. No patients with extensive disease survived for 5 years. This type of treatment has curative potential for SCLC limited disease, which calls for further trials based on this approach.

摘要

在6年期间,179例肺小细胞癌(SCLC)患者接受了胸部放疗以及环亚硝脲、阿霉素和长春花碱联合化疗,其中152例为局限性疾病,25例为广泛性疾病,2例未分期。所有患者的2年生存率为19.9%±3%,5年生存率为11.9%±3%。没有广泛性疾病患者存活5年。这种治疗方法对局限性疾病的SCLC具有治愈潜力,需要基于此方法进行进一步试验。

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