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Virus drug-resistance: mechanisms and consequences.

作者信息

Larder B A, Darby G

出版信息

Antiviral Res. 1984 Apr;4(1-2):1-42. doi: 10.1016/0166-3542(84)90023-8.

DOI:10.1016/0166-3542(84)90023-8
PMID:6331303
Abstract
摘要

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1
Virus drug-resistance: mechanisms and consequences.病毒耐药性:机制与后果
Antiviral Res. 1984 Apr;4(1-2):1-42. doi: 10.1016/0166-3542(84)90023-8.
2
Genetic mechanisms of resistance to acyclovir in herpes simplex virus.单纯疱疹病毒对阿昔洛韦耐药的遗传机制。
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Prophylaxis: a strategy to minimise antiviral resistance.
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Drug-resistant herpes simplex virus in vitro and after acyclovir treatment in an immunocompromised patient.免疫功能低下患者体内耐阿昔洛韦的单纯疱疹病毒及其体外研究
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Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci.单纯疱疹病毒对阿昔洛韦的耐药性:病毒胸苷激酶和DNA聚合酶基因座的作用。
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Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.在小鼠模型中,低水平的单纯疱疹病毒胸苷 - 胸苷酸激酶对某些抗病毒药物的敏感性或潜伏状态并无限制作用。
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Combination of ganciclovir and trifluridine prevents drug-resistance emergence in HSV-1.更昔洛韦联合三氟胸苷可预防 HSV-1 耐药性的产生。
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Penciclovir susceptibilities of herpes simplex virus isolates from patients using penciclovir cream for treatment of recurrent herpes labialis.使用喷昔洛韦乳膏治疗复发性唇疱疹的患者单纯疱疹病毒分离株的喷昔洛韦敏感性
Antimicrob Agents Chemother. 2002 Sep;46(9):2848-53. doi: 10.1128/AAC.46.9.2848-2853.2002.
3
Efficacies of gel formulations containing foscarnet, alone or combined with sodium lauryl sulfate, against establishment and reactivation of latent herpes simplex virus type 1.
膦甲酸钠凝胶制剂单独或与十二烷基硫酸钠联合使用对潜伏性单纯疱疹病毒1型的建立和再激活的疗效。
Antimicrob Agents Chemother. 2001 Apr;45(4):1030-6. doi: 10.1128/AAC.45.4.1030-1036.2001.
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Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues.用于评估临床单纯疱疹病毒分离株对核苷类似物耐药性的高度可靠的异源系统。
J Virol. 2001 Apr;75(7):3105-10. doi: 10.1128/JVI.75.7.3105-3110.2001.
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Characterization of herpes simplex viruses selected in culture for resistance to penciclovir or acyclovir.在培养中筛选出的对喷昔洛韦或阿昔洛韦耐药的单纯疱疹病毒的特性分析
J Virol. 2001 Feb;75(4):1761-9. doi: 10.1128/JVI.75.4.1761-1769.2001.
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Valaciclovir: a review of its long term utility in the management of genital herpes simplex virus and cytomegalovirus infections.伐昔洛韦:关于其在单纯疱疹病毒和巨细胞病毒感染管理中的长期效用综述。
Drugs. 2000 Apr;59(4):839-63. doi: 10.2165/00003495-200059040-00013.
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Survey of resistance of herpes simplex virus to acyclovir in northwest England.英格兰西北部单纯疱疹病毒对阿昔洛韦的耐药性调查。
Antimicrob Agents Chemother. 1998 Apr;42(4):868-72. doi: 10.1128/AAC.42.4.868.
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What clinicians need to know about antiviral drugs and viral resistance.临床医生需要了解的关于抗病毒药物和病毒耐药性的知识。
Infect Dis Clin North Am. 1997 Dec;11(4):945-67. doi: 10.1016/s0891-5520(05)70399-8.
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Valaciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in herpesvirus infections.伐昔洛韦。对其在疱疹病毒感染中的抗病毒活性、药代动力学特性及治疗效果的综述。
Drugs. 1996 Nov;52(5):754-72. doi: 10.2165/00003495-199652050-00009.
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Molecular analysis of a neurovirulent herpes simplex virus type 2 strain with reduced thymidine kinase activity.一株胸苷激酶活性降低的神经毒性2型单纯疱疹病毒的分子分析
Arch Virol. 1993;131(1-2):61-73. doi: 10.1007/BF01379080.