Reznikoff-Etievant M F, Edelman P, Muller J Y, Pinon F, Sureau C
Tissue Antigens. 1984 Jul;24(1):30-4. doi: 10.1111/j.1399-0039.1984.tb00394.x.
Antigen HLA-A, B sharing couples have been previously observed in abnormal pregnancies of unknown etiology. We have determined the HLA-A, B, C and DR antigens of 20 couples with recurrent spontaneous abortions (RSAs), 32 control couples and 100 normal controls. The results showed that in couples with more than two idiopathic repeated abortions, there is no significant increase in the HLA antigen sharing couples. But we were able to observe, in the affected couples, a significant increase in HLA-DR antigen sharing as regards the control couples. We also find a significant increase in the DR5 antigen, in both wives and husbands, in couples with repeated abortions of unknown etiology as previously described for the Dw5 antigen.
先前在病因不明的异常妊娠中观察到抗原HLA - A、B相同的夫妇。我们测定了20对复发性自然流产（RSA）夫妇、32对对照夫妇和100名正常对照者的HLA - A、B、C和DR抗原。结果显示，在有两次以上特发性反复流产的夫妇中，HLA抗原相同的夫妇数量没有显著增加。但我们观察到，与对照夫妇相比，受影响的夫妇中HLA - DR抗原相同的情况显著增加。我们还发现，在病因不明的反复流产夫妇中，妻子和丈夫的DR5抗原均显著增加，这与先前描述的Dw5抗原情况相同。
