Ray D K, Tendulkar J S, Shrivastava V B, Datta A K, Nagarajan K
J Antimicrob Chemother. 1984 Oct;14(4):423-6. doi: 10.1093/jac/14.4.423.
In the present study the comparative in-vitro and in-vivo efficacy of Go 10213 was compared with those of metronidazole, secnidazole, tinidazole, ornidazole and nimorazole against a metronidazole-resistant strain of T. vaginalis. Go 10213 was found to be superior in activity. It appears more promising than the drugs mentioned above on the basis of the evidence presented.
在本研究中,将Go 10213与甲硝唑、塞克硝唑、替硝唑、奥硝唑和尼莫唑针对一株甲硝唑耐药的阴道毛滴虫进行了体外和体内疗效比较。结果发现Go 10213活性更强。根据所提供的证据,它似乎比上述药物更具前景。