Brook I, Yocum P
Arch Otolaryngol. 1984 Dec;110(12):803-5. doi: 10.1001/archotol.1984.00800380033009.
Tonsils were obtained from 22 young adults (mean age, 23 years) suffering from chronic tonsillitis. Mixed aerobic and anaerobic flora was obtained from core tonsillar cultures in all patients, yielding an average of 9.0 isolates (5.3 anaerobes and 3.7 aerobes) per specimen. The predominant anaerobic isolates were Bacteroides sp, Fusobacterium sp, and gram-positive cocci. The predominant aerobic isolates were alpha-hemolytic streptococci, Staphylococcus aureus, Branhamella catarrhalis, beta-hemolytic streptococci, and hemophilus sp. beta-Lactamase-production was noted in 32 isolates recovered from 18 tonsils (82%). These included all eight isolates of S aureus and five B fragilis, and 11 of 24 B melaninogenicus group (46%). Our findings indicate the polymicrobial nature of deep tonsillar flora in young adults with chronic tonsillitis, and demonstrate the presence of beta-lactamase-producing organisms in most of the patients.
从22名患有慢性扁桃体炎的年轻成年人（平均年龄23岁）身上获取扁桃体。所有患者的扁桃体核心培养物中均分离出需氧菌和厌氧菌混合菌群，每个样本平均分离出9.0株菌株（5.3株厌氧菌和3.7株需氧菌）。主要的厌氧菌分离株为拟杆菌属、梭杆菌属和革兰氏阳性球菌。主要的需氧菌分离株为α溶血性链球菌、金黄色葡萄球菌、卡他布兰汉菌、β溶血性链球菌和嗜血杆菌属。从18个扁桃体中分离出的32株菌株（82%）检测到β-内酰胺酶产生。其中包括所有8株金黄色葡萄球菌和5株脆弱拟杆菌，以及产黑色素拟杆菌群24株中的11株（46%）。我们的研究结果表明，患有慢性扁桃体炎的年轻成年人深部扁桃体菌群具有多微生物性质，并证明大多数患者体内存在产β-内酰胺酶的生物体。
