对17例慢性进行性系统性硬化症（PSS）患者和17例在性别、年龄及病程方面相匹配的CREST综合征患者进行临床和血清学比较。
Clinical and serological comparison of 17 chronic progressive systemic sclerosis (PSS) and 17 CREST syndrome patients matched for sex, age, and disease duration.
作者信息
Furst D E, Clements P J, Saab M, Sterz M G, Paulus H E
出版信息
Ann Rheum Dis. 1984 Dec;43(6):794-801. doi: 10.1136/ard.43.6.794.
Abstract
This study compares the clinical and serological differences between 17 PSS and 17 carefully matched CREST patients. Patients were matched for sex, age by decade, and, importantly, disease duration (11.2 +/- 9.2 vs. 12.0 +/- 9.3 years). Muscular and skin involvement were greater for the PSS groups (p less than 0.02) and pulmonary involvement was also greater (p less than 0.05), at least for non-smoking PSS patients. On the other hand no clinically significant differences were found between groups for other visceral involvement--including comparisons of gastrointestinal, cardiovascular, and renal involvement. There were also no laboratory differences except in anti-RNP antibody (p less than 0.04).
摘要
本研究比较了17例系统性硬化症（PSS）患者和17例精心匹配的CREST综合征患者的临床和血清学差异。患者在性别、按十年划分的年龄方面进行了匹配，重要的是，疾病持续时间也相匹配（分别为11.2±9.2年和12.0±9.3年）。PSS组的肌肉和皮肤受累情况更严重（p<0.02），肺部受累情况也更严重（p<0.05），至少对于不吸烟的PSS患者是这样。另一方面，在其他内脏受累方面，包括胃肠道、心血管和肾脏受累的比较，两组之间未发现临床上的显著差异。除了抗RNP抗体外，实验室检查也没有差异（p<0.04）。
相似文献
1
Clinical and serological comparison of 17 chronic progressive systemic sclerosis (PSS) and 17 CREST syndrome patients matched for sex, age, and disease duration.对17例慢性进行性系统性硬化症（PSS）患者和17例在性别、年龄及病程方面相匹配的CREST综合征患者进行临床和血清学比较。
Ann Rheum Dis. 1984 Dec;43(6):794-801. doi: 10.1136/ard.43.6.794.
2
Association of antinuclear and antinucleolar antibodies in progressive systemic sclerosis.进行性系统性硬化症中抗核抗体与抗核仁抗体的关联。
Clin Exp Immunol. 1982 Apr;48(1):43-51.
3
Clinical and laboratory associations of anticentromere antibody in patients with progressive systemic sclerosis.进行性系统性硬化症患者抗着丝点抗体的临床和实验室关联
Arthritis Rheum. 1984 Feb;27(2):125-31. doi: 10.1002/art.1780270202.
4
[The CREST syndrome. Apropos of a case with Wolff-Parkinson-White type B syndrome].[CREST综合征。关于一例B型预激综合征的病例]
Tunis Med. 1988 May;66(5):481-3.
5
Pulmonary hypertension in the CREST syndrome: variant of systemic sclerosis (scleroderma)--a case report.CREST综合征中的肺动脉高压：系统性硬化症（硬皮病）的一种变体——病例报告
Angiology. 1989 Aug;40(8):764-7. doi: 10.1177/000331978904000812.
6
Scleroderma and urinary excretion of acidic glycosaminoglycans.硬皮病与酸性糖胺聚糖的尿排泄
Mayo Clin Proc. 1971 Feb;46(2):119-27.
7
[Pathogenetic observations apropos of an association of Crest's syndrome and Gougerot-Sjögren's syndrome].关于CREST综合征与舍格伦综合征关联的发病机制观察
Rev Rhum Mal Osteoartic. 1975 Feb;42(2):127-30.
8
Antinuclear antibodies as immunologic markers for a benign subset and different clinical characteristics of scleroderma.
Arch Dermatol. 1982 Nov;118(11):882-5.
9
A controlled clinicopathologic study of myocardial fibrosis in systemic sclerosis (scleroderma).系统性硬化症（硬皮病）中心肌纤维化的对照临床病理研究
J Rheumatol. 1990 May;17(5):656-62.
10
Renal vascular histology and morphometry in systemic sclerosis. A case-control autopsy study.系统性硬化症的肾血管组织学与形态计量学。一项病例对照尸检研究。
Arthritis Rheum. 1988 Mar;31(3):393-400. doi: 10.1002/art.1780310311.
引用本文的文献
1
The Unusual Suspect: An Acute Gastric Dilation With Volvulus in a Scleroderma Patient.异常病例：一名硬皮病患者出现急性胃扩张伴扭转
Cureus. 2022 Mar 24;14(3):e23436. doi: 10.7759/cureus.23436. eCollection 2022 Mar.
2
Dysphagia, reflux and related sequelae due to altered physiology in scleroderma.硬皮病导致的生理学改变引起的吞咽困难、反流和相关后遗症。
World J Gastroenterol. 2021 Aug 21;27(31):5201-5218. doi: 10.3748/wjg.v27.i31.5201.
3
Gastrointestinal Manifestations of Systemic Sclerosis.系统性硬化症的胃肠道表现
Rheumatology (Sunnyvale). 2018;8(1). doi: 10.4172/2161-1149.1000235. Epub 2018 Mar 30.
4
Preliminary study of cardiovascular manifestations and cardiac severity scale in 58 patients with systemic sclerosis in iran using the medsger scale.使用梅兹格量表对伊朗58例系统性硬化症患者心血管表现及心脏严重程度量表的初步研究。
J Tehran Heart Cent. 2010 Winter;5(1):14-8. Epub 2010 Feb 28.
5
Dexamethasone pulse therapy in patients of systemic sclerosis: is it a viable proposition? A study from kashmir.全身硬化症患者的地塞米松脉冲疗法：这是一个可行的方案吗？来自克什米尔的一项研究。
Indian J Dermatol. 2010 Oct;55(4):355-8. doi: 10.4103/0019-5154.74543.
6
Sclerodactyly, CREST syndrome, proximal scleroderma.硬皮病指（趾）、CREST综合征、近端硬皮病。
Ann Rheum Dis. 1986 Jan;45(1):86. doi: 10.1136/ard.45.1.86-a.
7
A new promising treatment in systemic sclerosis: 5-fluorouracil.系统性硬化症的一种新的有前景的治疗方法：5-氟尿嘧啶。
Ann Rheum Dis. 1987 Oct;46(10):763-7. doi: 10.1136/ard.46.10.763.
8
Scleroderma esophagus.
Dysphagia. 1990;5(4):204-10. doi: 10.1007/BF02412688.
本文引用的文献
1
The CREST syndrome: a distinct serologic entity with anticentromere antibodies.CREST综合征：一种具有抗着丝点抗体的独特血清学实体。
Am J Med. 1980 Oct;69(4):520-6. doi: 10.1016/0002-9343(80)90462-3.
2
Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis.进行性系统性硬化症中肺动脉高压的患病率及临床相关性
Am J Med. 1983 Jul;75(1):65-74. doi: 10.1016/0002-9343(83)91169-5.
3
CRST syndrome. A benign variant of scleroderma.CRST综合征。硬皮病的一种良性变异型。
Arch Dermatol. 1965 Nov;92(5):519-25. doi: 10.1001/archderm.92.5.519.
4
Pulmonary hypertension in systemic sclerosis.系统性硬化症中的肺动脉高压。
Ann Rheum Dis. 1971 Jul;30(4):390-400. doi: 10.1136/ard.30.4.390.
5
Pulmonary hypertension in the CREST syndrome variant of progressive systemic sclerosis (scleroderma).进行性系统性硬化症（硬皮病）CREST综合征变异型中的肺动脉高压。
Ann Intern Med. 1977 Apr;86(4):394-9. doi: 10.7326/0003-4819-86-4-394.
6
The 'CREST' syndrome. Comparison with systemic sclerosis (scleroderma).“CREST”综合征。与系统性硬化症（硬皮病）的比较。
Arch Intern Med. 1979 Nov;139(11):1240-4. doi: 10.1001/archinte.139.11.1240.
Zotero 插件