Iacono J M, Puska P, Dougherty R M
Ann Clin Res. 1984;16 Suppl 43:116-25.
The role of dietary fat in the origin of human hypertension has aroused interest recently. Results from five intervention studies and from a cross-sectional international study are presented. Three of the intervention studies were carried out in Beltsville, Maryland, USA, and two were carried out in North Karelia, Finland. All the studies involved healthy people and diets typical of the areas concerned. During the experimental periods the diets were modified in such a way that the energy percentage from fats was lowered and the P/S ratio raised. Energy and salt intake were kept constant. The results showed that the blood pressure levels were consistently changed using various dietary fat modifications. The results give strong support to the hypothesis that dietary fat is associated with blood pressure.
膳食脂肪在人类高血压发病中的作用最近引起了人们的关注。本文呈现了五项干预研究以及一项横断面国际研究的结果。其中三项干预研究在美国马里兰州的贝尔茨维尔进行,两项在芬兰的北卡累利阿进行。所有研究均涉及健康人群以及相关地区典型的饮食。在实验期间,对饮食进行了调整,降低了脂肪提供的能量百分比并提高了多不饱和脂肪酸与饱和脂肪酸的比例。能量和盐的摄入量保持恒定。结果表明,通过对膳食脂肪进行各种调整,血压水平持续发生了变化。这些结果有力地支持了膳食脂肪与血压相关的假说。