Iacono J M, Dougherty R M, Puska P
Can J Physiol Pharmacol. 1986 Jun;64(6):856-62. doi: 10.1139/y86-148.
The role of dietary fat in human hypertension has been of interest recently. Examples of two intervention studies are presented to demonstrate this effect. One study was conducted at Beltsville, MD, and the other at North Karelia, Finland. Healthy people served as subjects for the experiments and the foods consumed by the subjects were typical for the regions. During the intervention periods the percentage of energy from dietary fats was lowered while the polyunsaturated fatty acids were increased. Total energy intake and salt intake were kept relatively constant. Systolic and diastolic blood pressure were decreased during the lowered fat, higher polyunsaturated fatty acids intake period and this effect was reversed during the switchback period. The data give strong support to the hypothesis that dietary fat is associated with blood pressure.
膳食脂肪在人类高血压中的作用近来备受关注。现列举两项干预研究的实例来证明这种作用。一项研究在马里兰州的贝尔茨维尔进行,另一项在芬兰的北卡累利阿进行。健康人群作为实验对象,他们所食用的食物是这些地区的典型食物。在干预期间,膳食脂肪提供的能量百分比降低,同时多不饱和脂肪酸增加。总能量摄入和盐摄入量保持相对稳定。在脂肪摄入量降低、多不饱和脂肪酸摄入量增加的时期,收缩压和舒张压下降,而在恢复原饮食的时期,这种效果则逆转。这些数据有力地支持了膳食脂肪与血压有关这一假说。