Melton L J, Ochi J W, Palumbo P J, Chu C P
Department of Medical Statistics and Epidemiology, Mayo Clinic, Rochester, Minnesota 55905.
Diabetes Care. 1983 Sep-Oct;6(5):427-31. doi: 10.2337/diacare.6.5.427.
In a population-based study in Rochester, Minnesota, the clinical characteristics of 1135 patients newly diagnosed with diabetes (1945-69) were compared with those of 810 residents with diabetes mellitus on prevalence day (1 January 1970). The prevalence patients were older and the male: female ratio was reduced from that seen among incidence cases. The prevalence patients were more likely to be on oral agents, had lower fasting blood glucose levels, were less likely to be symptomatic, but were more likely to have macrovascular and microvascular complications. These differences seemed to come about as a result of variation in survival rates among patients with specific characteristics, differential migration of certain groups of patients, and changes in the status of individuals.
在明尼苏达州罗切斯特市开展的一项基于人群的研究中,对1945年至1969年期间新诊断为糖尿病的1135例患者与糖尿病患病率调查日(1970年1月1日)的810例糖尿病居民的临床特征进行了比较。患病率调查对象年龄更大,男女比例低于新发病例。患病率调查对象更有可能接受口服药物治疗,空腹血糖水平较低,出现症状的可能性较小,但发生大血管和微血管并发症的可能性更大。这些差异似乎是由于具有特定特征的患者生存率不同、某些患者群体的差异迁移以及个体状况变化所致。