Oldridge N B, Donner A P, Buck C W, Jones N L, Andrew G M, Parker J O, Cunningham D A, Kavanagh T, Rechnitzer P A, Sutton J R
Am J Cardiol. 1983 Jan 1;51(1):70-4. doi: 10.1016/s0002-9149(83)80013-7.
The Ontario Exercise-Heart Collaborative Study was a multicenter randomized clinical trial of high intensity exercise for the prevention of recurrent myocardial infarction in 733 men. Of the 678 subjects who could have participated for at least 3 years, 315 (46.5%) dropped out. Stepwise multiple linear logistic regression analysis was carried out to examine the relation between subject characteristics and the probability of dropping out during the study. Analysis was performed on the entry group as a whole by considering those subjects who had reinfarction while complying with the program and also by excluding all subjects with reinfarctions. The consistent and statistically significant predictors of dropout in both analyses were smoking and a blue collar occupation. Angina was significantly associated with dropout only when reinfarctions were excluded. It may be important to consider these factors when investigating the potential for compliance-improving strategies in reducing dropout from exercise rehabilitation programs.
安大略运动-心脏协作研究是一项多中心随机临床试验，旨在对733名男性进行高强度运动以预防复发性心肌梗死。在本可参与至少3年的678名受试者中，有315名（46.5%）退出。进行了逐步多元线性逻辑回归分析，以研究受试者特征与研究期间退出可能性之间的关系。对整个入组人群进行分析时，考虑了那些在遵守方案期间再次梗死的受试者，也排除了所有再次梗死的受试者。在两项分析中，一致且具有统计学意义的退出预测因素是吸烟和蓝领职业。仅在排除再次梗死的受试者后，心绞痛才与退出显著相关。在研究改善依从性策略以减少运动康复计划中退出情况的可能性时，考虑这些因素可能很重要。
