抗白血病生物碱2-羟基-3,8,9-三甲氧基-5-甲基苯并[c]菲啶（法卡林二醇）与核酸的相互作用。 - Suppr

Suppr

超能文献

Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids.

作者信息

Pezzuto J M, Antosiak S K, Messmer W M, Slaytor M B, Honig G R

出版信息

Chem Biol Interact. 1983 Mar;43(3):323-39. doi: 10.1016/0009-2797(83)90116-3.

DOI:10.1016/0009-2797(83)90116-3

PMID:6337734

Abstract

摘要

相似文献

Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids.抗白血病生物碱2-羟基-3,8,9-三甲氧基-5-甲基苯并[c]菲啶（法卡林二醇）与核酸的相互作用。

Chem Biol Interact. 1983 Mar;43(3):323-39. doi: 10.1016/0009-2797(83)90116-3.

Effect of fagaronine on chromosome breaks and loss in Drosophila melanogaster.法加罗宁对黑腹果蝇染色体断裂和丢失的影响。

Mutat Res. 1987 Aug;188(4):307-9. doi: 10.1016/0165-1218(87)90007-3.

Absence of mutagenicity of benzo[c]phenanthridine alkaloids in somatic cells of Drosophila melanogaster: comparison with 7,12-dimethylbenz[a]anthracene and chrysene.苯并[c]菲啶生物碱在黑腹果蝇体细胞中无致突变性：与7,12-二甲基苯并[a]蒽和 Chrysene 的比较。

Mutat Res. 1993 Feb;298(4):277-83. doi: 10.1016/0165-1218(93)90007-z.

The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.抗白血病生物碱法格任宁是DNA拓扑异构酶I和II的抑制剂。

Biochem Pharmacol. 1993 Oct 19;46(8):1403-12. doi: 10.1016/0006-2952(93)90105-6.

The antileukemic alkaloid fagaronine and the human K 562 leukemic cells: effects on growth and induction of erythroid differentiation.抗白血病生物碱法格龙宁与人类K562白血病细胞：对生长及红系分化诱导的影响

Leuk Res. 1987;11(5):445-51. doi: 10.1016/0145-2126(87)90076-2.

Synthesis and cytotoxic activities of a new benzo[c]phenanthridine alkaloid, 7-hydroxynitidine, and some 9-oxygenated benzo[c]phenanthridine derivatives.一种新型苯并[c]菲啶生物碱7-羟基氯化两面针碱及一些9-氧化苯并[c]菲啶衍生物的合成与细胞毒活性

Org Lett. 1999 Oct 7;1(7):985-8. doi: 10.1021/ol990775g.

Molecular determinants of site-specific inhibition of human DNA topoisomerase I by fagaronine and ethoxidine. Relation to DNA binding.法加罗宁和乙氧啶对人DNA拓扑异构酶I位点特异性抑制的分子决定因素。与DNA结合的关系。

J Biol Chem. 2000 Feb 4;275(5):3501-9. doi: 10.1074/jbc.275.5.3501.

Effects of the antitumor drugs 3-nitrobenzothiazolo[3,2-alpha]quinolinium and fagaronine on nucleic acid and protein synthesis.抗肿瘤药物3-硝基苯并噻唑并[3,2-α]喹啉鎓和白屈菜红碱对核酸和蛋白质合成的影响。

Biochem Pharmacol. 1986 Feb 15;35(4):679-85. doi: 10.1016/0006-2952(86)90367-9.

Effects of ascorbic acid on the nonenzymatic binding to DNA and the mutagenicity of N-hydroxylated metabolite of a tryptophan-pyrolysis product.抗坏血酸对色氨酸热解产物的N-羟基化代谢物与DNA的非酶结合及致突变性的影响。

Biochem Biophys Res Commun. 1982 Apr 29;105(4):1396-401. doi: 10.1016/0006-291x(82)90942-1.

Studies on the chemical constituents of rutaceous plants. LX. Development of a versatile method for syntheses of the antitumor benzo[c]phenanthridine alkaloids. (9). Efficient syntheses and antitumor activities of nitidine and related nonphenolic benzo[c]phenanthridine alkaloids.芸香科植物化学成分的研究。LX. 一种通用的抗肿瘤苯并[c]菲啶生物碱合成方法的开发。(9). 氧化苦参碱及相关非酚性苯并[c]菲啶生物碱的高效合成与抗肿瘤活性。

Chem Pharm Bull (Tokyo). 1985 Oct;33(10):4139-51. doi: 10.1248/cpb.33.4139.

引用本文的文献

Biophysical aspects and biological implications of the interaction of benzophenanthridine alkaloids with DNA.苯并菲啶生物碱与DNA相互作用的生物物理方面及生物学意义。

Biophys Rev. 2009 Sep;1(3):119-129. doi: 10.1007/s12551-009-0014-7. Epub 2009 Aug 25.

In vitro antiplasmodial activity of some medicinal plants of Burkina Faso.布基纳法索部分药用植物的抗疟原虫体外活性

Parasitol Res. 2014 Jan;113(1):405-16. doi: 10.1007/s00436-013-3669-8. Epub 2013 Dec 8.

Natural-product inhibitors of human DNA ligase I.人类DNA连接酶I的天然产物抑制剂。

Biochem J. 1996 Mar 15;314 ( Pt 3)(Pt 3):993-1000. doi: 10.1042/bj3140993.

Kmeriol and other aromatic constituents of Kmeria duperreana.华盖木中的华盖木酚及其他芳香成分。

Pharm Res. 1989 Jul;6(7):637-40. doi: 10.1023/a:1015969902200.

Comparative effects of fagaronine, adriamycin and aclacinomycin on K562 cell sensitivity to natural-killer-mediated lysis. Lack of agreement between alteration of transferrin receptor and CD15 antigen expressions and induction of resistance to natural killer.白屈菜红碱、阿霉素和阿克拉霉素对K562细胞自然杀伤细胞介导的细胞溶解敏感性的比较效应。转铁蛋白受体和CD15抗原表达的改变与对自然杀伤细胞抗性诱导之间缺乏一致性。

Cancer Immunol Immunother. 1989;30(5):289-94. doi: 10.1007/BF01744896.

Sesquiterpene lactones and other constituents from a cytotoxic extract of Michelia floribunda.含笑花细胞毒性提取物中的倍半萜内酯及其他成分。

Pharm Res. 1990 Dec;7(12):1269-72. doi: 10.1023/a:1015937921880.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验