Easmon C S, Hastings M J, Blowers A, Bloxham B, Deeley J, Marwood R, Rivers R P, Stringer J
Br J Obstet Gynaecol. 1983 Mar;90(3):241-6. doi: 10.1111/j.1471-0528.1983.tb08617.x.
The epidemiology of group B streptococci (GBS) was studied in an obstetric unit and the related special care baby unit (SCBU). In 1 year 53 (77%) of 69 babies who acquired GBS from their mothers were colonized within 24 h of birth, compared with only 9 (35%) of 38 who acquired GBS from non-maternal sources. While 38 (36%) of 107 GBS colonized babies in the obstetric unit derived the organism from a non-maternal source, the value for the SCBU was only 2 (9%) of 23. In babies rectal and umbilical swabs gave the highest GBS isolation rates. Phage-typing and serotyping suggested that colonized mother baby pairs, rather than staff, were the primary source of hospital acquired GBS. This mode of GBS acquisition did not result in long-term carriage once babies had left hospital. Nosocomial transmission can play an important part in GBS epidemiology, but can be minimized by attention to infection control procedures.
在一个产科病房及相关的新生儿重症监护病房（SCBU）对B族链球菌（GBS）的流行病学进行了研究。在1年的时间里，69例从母亲那里获得GBS的婴儿中有53例（77%）在出生后24小时内被定植，相比之下，38例从非母亲来源获得GBS的婴儿中只有9例（35%）在出生后24小时内被定植。在产科病房的107例GBS定植婴儿中，有38例（36%）从非母亲来源获得该病菌，而在新生儿重症监护病房，这一比例在23例中仅为2例（9%）。在婴儿中，直肠和脐部拭子的GBS分离率最高。噬菌体分型和血清分型表明，定植的母婴对而非工作人员是医院获得性GBS的主要来源。一旦婴儿出院，这种获得GBS的方式不会导致长期携带。医院内传播在GBS流行病学中可能起重要作用，但通过注意感染控制程序可将其降至最低。
