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全身γ辐射对大鼠组织中还原型谷胱甘肽含量的影响。

Effect of whole body gamma radiation on reduced glutathione contents of rat tissues.

作者信息

Sarkar S R, Singh L R, Uniyal B P, Chaudhuri B N

出版信息

Strahlentherapie. 1983 Jan;159(1):32-3.

PMID:6340248
Abstract

Reduced glutathione (GSH) contents of blood, heart, liver and spleen were studied after one, four and seven days of irradiation in rats. Blood GSH in rats exposed to 4 Gy remained unaltered throughout, while animals exposed to 8 Gy showed significant decrease of blood GSH on the 8th day after exposure. Diminution of liver and heart GSH contents was observed initially in both groups of irradiated rats, while the reverse was noted in spleen GSH contents of experimental animals.

摘要

研究了大鼠在照射1天、4天和7天后血液、心脏、肝脏和脾脏中还原型谷胱甘肽(GSH)的含量。暴露于4 Gy的大鼠血液GSH在整个过程中保持不变,而暴露于8 Gy的动物在暴露后第8天血液GSH显著降低。在两组受照射大鼠中,最初均观察到肝脏和心脏GSH含量减少,而实验动物脾脏GSH含量则相反。

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