特邀综述。神经系统抗原。
Invited review. Nervous system antigens.
作者信息
Graham D I, Thomas D G, Brown I
出版信息
Histopathology. 1983 Jan;7(1):1-21. doi: 10.1111/j.1365-2559.1983.tb02212.x.
Some of the better characterized proteins (markers) of the nervous system are described. The availability of specific antibodies to these markers has allowed the localization and assay of the proteins in tissue and biological fluids. There is some evidence that autosensitization may occur. Clinical application of these markers includes the evaluation and prognostic significance after stroke and head injury. The diagnostic histopathological use of the markers in the investigation of various tumours is summarized.
本文描述了一些神经系统中特征较为明确的蛋白质（标志物）。针对这些标志物的特异性抗体的可得性使得能够在组织和生物体液中对这些蛋白质进行定位和检测。有证据表明可能会发生自身致敏。这些标志物的临床应用包括中风和头部受伤后的评估及预后意义。总结了这些标志物在各种肿瘤研究中的诊断组织病理学用途。
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