Zabel M, Surdyk J, Biela-Jacek I
Histochemistry. 1986;86(1):97-9. doi: 10.1007/BF00492351.
The distribution of S-100 protein in the parathyroid cells of normal and hypercalcaemic rats and guinea pigs was investigated. Previous studies had shown that the applied antibodies detect only the beta subunit of S-100 protein. S-100 protein was found in all parathyroid cells of rats aged between 1 and 720 days. In adult guinea pigs, S-100 protein was detectable in only a small proportion of parathyroid cells. The level of S-100 protein in individual cells exhibited considerable variation, particularly in guinea pig. Hypercalcaemia did not affect the distribution of S-100 protein in the parathyroid cells of either rats or guinea pigs. In both species, the presence of small groups of parathyroid cells in the central fragments of thyroid lobes was often noted.
研究了正常和高钙血症大鼠及豚鼠甲状旁腺细胞中S - 100蛋白的分布情况。先前的研究表明，所应用的抗体仅检测S - 100蛋白的β亚基。在1至720日龄大鼠的所有甲状旁腺细胞中均发现了S - 100蛋白。在成年豚鼠中，仅在一小部分甲状旁腺细胞中可检测到S - 100蛋白。单个细胞中S - 100蛋白的水平表现出相当大的差异，尤其是在豚鼠中。高钙血症并不影响大鼠或豚鼠甲状旁腺细胞中S - 100蛋白的分布。在这两个物种中，经常注意到甲状腺叶中央部分存在小群甲状旁腺细胞。
