Essex M, McLane M F, Lee T H, Falk L, Howe C W, Mullins J I, Cabradilla C, Francis D P
Science. 1983 May 20;220(4599):859-62. doi: 10.1126/science.6342136.
The acquired immune deficiency syndrome (AIDS), which has recently occurred at increasing rates in homosexual men, intravenous drug users, and others, is characterized by the development of Kaposi's sarcoma and several opportunistic infections including pneumonia caused by Pneumocystis carinii. Serum samples from patients with AIDS and from matched and unmatched control subjects were examined for the presence of antibodies to cell membrane antigens associated with human T-cell leukemia virus. Nineteen of 75 of the AIDS patients had antibodies directed to surface antigens of Hut 102, a reference T lymphoid cell line infected with leukemia virus, as did two of the 336 control subjects.
获得性免疫缺陷综合征（艾滋病）最近在同性恋男性、静脉吸毒者及其他人群中的发病率呈上升趋势，其特征为卡波西肉瘤的发展以及包括卡氏肺囊虫肺炎在内的几种机会性感染。对艾滋病患者以及匹配和不匹配的对照受试者的血清样本进行检测，以查找与人类T细胞白血病病毒相关的细胞膜抗原抗体。75名艾滋病患者中有19名具有针对感染白血病病毒的参考T淋巴细胞系Hut 102表面抗原的抗体，336名对照受试者中有2名也有此类抗体。
