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去甲氧基雷帕霉素(AY - 24,668),一种新型抗真菌抗生素。

Demethoxyrapamycin (AY-24,668), a new antifungal antibiotic.

作者信息

Sehgal S N, Baker H, Eng C P, Singh K, Vézina C

出版信息

J Antibiot (Tokyo). 1983 Apr;36(4):351-4. doi: 10.7164/antibiotics.36.351.

Abstract

Demethoxyrapamycin is a new antifungal antibiotic which is co-produced with rapamycin by Streptomyces hygroscopicus. It was isolated as a minor component during recovery of rapamycin. Its antifungal and antitumor activity is compared with that of rapamycin.

摘要

去甲氧基雷帕霉素是一种新的抗真菌抗生素,它由吸水链霉菌与雷帕霉素共同产生。在雷帕霉素的回收过程中,它作为次要成分被分离出来。将其抗真菌和抗肿瘤活性与雷帕霉素进行了比较。

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