Cowley J G
Neoplasma. 1978;25(1):83-90.
A cytologic and proliferation analysis was performed in the lymph node samples of 30 nontreated Hodgkin patients using tritiated thymidine, the autoradiographic technique, and two different in vitro incubation schemes. A group of 9 inflammatory reactive patients was used as control. The results confirmed previous labeling data but showed that DNA synthesis can also be detected among the reticulum cells. The role attributed by some authors to the large rounded basophilic cells of lymphoid appearance found in Hodgkin's tissue is discussed in the light of the results in Hodgkin's and non Hodgkin's samples. Finally, some aspects dealing with the relationship and possible role of the Hodgkin and Sternberg-Reed cells are commented.
使用氚标记胸腺嘧啶核苷、放射自显影技术以及两种不同的体外培养方案，对30例未经治疗的霍奇金病患者的淋巴结样本进行了细胞学和增殖分析。选取9例炎症反应性患者作为对照组。结果证实了先前的标记数据，但显示在网状细胞中也可检测到DNA合成。根据霍奇金病和非霍奇金病样本的结果，讨论了一些作者赋予霍奇金组织中发现的具有淋巴细胞样外观的大圆形嗜碱性细胞的作用。最后，对涉及霍奇金细胞和施特恩伯格-里德细胞的关系及可能作用的一些方面进行了评论。
