Togari H, Mikawa M, Iwanaga T, Matsumoto N, Kawase A, Hagisawa M, Ogino T, Goto R, Watanabe I, Kito H, Ogawa Y, Wada Y
Acta Paediatr Scand. 1983 Jan;72(1):87-91. doi: 10.1111/j.1651-2227.1983.tb09669.x.
The role of exchange transfusion with fresh whole blood in septic shock infants was evaluated. Endotoxin was positive in 8 of 10 infants and completely removed from 6 by exchange transfusion. All 6 infants with negative endotoxins after exchange transfusions survived, but 2 with positive reactions died despite the exchange transfusion. Staphylococcus aureus was cultured in the blood from 2 infants with negative reactions and one of them survived. These findings suggested that the clearance of endotoxin has an important role in exchange transfusion among septic shock neonates.
