McDonald J C, Rohr M S, Tucker W Y
Ann Surg. 1983 Jun;197(6):678-87. doi: 10.1097/00000658-198306000-00006.
Ten autotransplants are presented. Renal autografts were performed in the correction of renal artery stenosis, renal artery aneurysm, and intrarenal arteriovenous fistula. All were successful. Jejunal autografts were used to replace the cervical esophagus twice and the entire esophagus once. All grafts were successful, although one patient with advanced cancer died. Pancreatic segmental autografts were used to prevent diabetes following three subtotal pancreatectomies for chronic pancreatitis and one total pancreatectomy for carcinoma. Two patients have functioning grafts, require no insulin, and are free of disease at present. One patient is free of pancreatitis but is diabetic, and one patient died of probable pulmonary embolus. These experiences suggest that organ autografts can be used with greater frequency in clinical surgery and may alter standard therapy for several problems.
本文展示了十例自体移植病例。肾自体移植用于纠正肾动脉狭窄、肾动脉动脉瘤和肾内动静脉瘘,所有手术均获成功。空肠自体移植两次用于替代颈段食管,一次用于替代整个食管。尽管有一名晚期癌症患者死亡,但所有移植均成功。胰腺节段自体移植用于在三例因慢性胰腺炎行胰次全切除术和一例因癌行全胰切除术后预防糖尿病。两名患者的移植功能良好,无需胰岛素,目前无疾病。一名患者无胰腺炎但患有糖尿病,一名患者可能死于肺栓塞。这些经验表明,器官自体移植在临床手术中可以更频繁地使用,并且可能改变一些疾病的标准治疗方法。