饮食微小变化导致聚乙烯吡咯烷酮清除率和免疫反应性改变。
Altered polyvinylpyrrolidone clearance and immune responsiveness caused by small dietary changes.
作者信息
Newby T J, Stokes C R, Bourne F J
出版信息
Clin Exp Immunol. 1980 Feb;39(2):349-54.
Abstract
The introduction of 25 mg of a new protein antigen into the diets of mice produced transient increases in PVP clearance which reached a maximum 60 hr after the change of diet and had disappeared by 4 days. At the same time the immune responsiveness to unrelated antigens given parenterally was also raised transiently, reaching a peak 5 days following the change and disappearing by 7 days. In contrast the responsiveness to the fed antigen was diminished.
摘要
给小鼠饮食中添加25毫克一种新的蛋白质抗原，会使聚乙烯吡咯烷酮（PVP）清除率出现短暂升高，在饮食改变后60小时达到峰值，并在4天后消失。与此同时，对通过非肠道途径给予的无关抗原的免疫反应性也会短暂提高，在饮食改变后5天达到峰值，并在7天后消失。相比之下，对喂食抗原的反应性则降低。
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本文引用的文献
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Plaque formation in agar by single antibody-producing cells.单个产生抗体的细胞在琼脂中形成菌斑。
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