Fieschi C, Orzi F, Pocchiari M, Nardini M, Rocchi F, Asher D, Gibbs C, Gajdusek D
Ital J Neurol Sci. 1983 Apr;4(1):61-4. doi: 10.1007/BF02043438.
Two cases of histopathologically documented Creutzfeldt-Jakob disease were observed in the same area of the province of Siena in 1974-1975. The transmission of the disease was obtained through brain homogenates and lymphnodes in one of the two cases. This confirms that the agent is present in other tissues besides the brain and underlines further the analogies between Creutzfeld-Jakob disease and scrapie.
1974年至1975年期间,在锡耶纳省的同一地区观察到两例经组织病理学确诊的克雅氏病。在其中一例中,通过脑匀浆和淋巴结实现了疾病传播。这证实了该病原体除了在脑中存在外,还存在于其他组织中,并进一步强调了克雅氏病与羊瘙痒症之间的相似性。