Amemiya T, Toibana M, Hashimoto M, Oseko F, Imura H
Ophthalmologica. 1978;176(2):74-80. doi: 10.1159/000308696.
A study was made of diabetic retinopathy in acromegaly. 10 of 15 patients with acromegaly had diabetes mellitus, and 3 of the 10 showed diabetic retinopathy. 2 of them had a diabetic family history. 1 patient with a diabetic family history had retinopathy of state IIIa in Scott's classification, and the other 2 showed a few microaneurysms and/or punctate hemorrhages in the macula. Diabetes mellitus and diabetic retinopathy in acromegaly showed no correlation with the duration of acromegaly and diabetes mellitus, age, or growth hormone level. No diabetic cataract was found in the present series. It was concluded that diabetic retinopathy due to secondary diabetes mellitus is usually slight or moderate. Diabetes mellitus with severe retinopathy is probably primary diabetes due to a genetic defect, and secondary diabetes may be different in nature from the primary disease.
对肢端肥大症患者的糖尿病视网膜病变进行了一项研究。15例肢端肥大症患者中有10例患有糖尿病，其中3例出现糖尿病视网膜病变。他们中有2例有糖尿病家族史。1例有糖尿病家族史的患者在斯科特分类中处于IIIa期视网膜病变，另外2例在黄斑区有一些微动脉瘤和/或点状出血。肢端肥大症中的糖尿病和糖尿病视网膜病变与肢端肥大症和糖尿病的病程、年龄或生长激素水平均无相关性。本系列中未发现糖尿病性白内障。得出的结论是，继发性糖尿病所致的糖尿病视网膜病变通常为轻度或中度。伴有严重视网膜病变的糖尿病可能是由遗传缺陷导致的原发性糖尿病，继发性糖尿病在本质上可能与原发性疾病不同。
