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C型肉毒梭菌孢子提取物中的C2毒性

C2 toxicity in extract of Clostridium botulinum type C spores.

作者信息

Yamakawa K, Nishida S, Nakamura S

出版信息

Infect Immun. 1983 Aug;41(2):858-60. doi: 10.1128/iai.41.2.858-860.1983.

DOI:10.1128/iai.41.2.858-860.1983
PMID:6347900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC264723/
Abstract

Toxic protein(s) neutralized with anti-C2 toxic serum was extracted from Clostridium botulinum type C spores treated with an alkaline mercaptoethanol solution. C2 toxicity in the spores was located in the spore coat fraction and was more heat stable than that found in culture fluid.

摘要

用抗C2毒素血清中和的有毒蛋白是从经碱性巯基乙醇溶液处理的C型肉毒梭菌孢子中提取的。孢子中的C2毒素位于孢子壁部分，比培养液中的毒素更耐热。

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引用本文的文献

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Toxins (Basel). 2014 Sep 5;6(9):2626-56. doi: 10.3390/toxins6092626.
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Microbiol Mol Biol Rev. 2004 Sep;68(3):373-402, table of contents. doi: 10.1128/MMBR.68.3.373-402.2004.
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Thermal sensitivity of Clostridium botulinum type C toxin.C型肉毒杆菌毒素的热敏感性
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本文引用的文献

1
Purification and characterization of two components of botulinum C2 toxin.肉毒杆菌C2毒素两种成分的纯化与特性分析
Infect Immun. 1980 Dec;30(3):668-73. doi: 10.1128/iai.30.3.668-673.1980.
2
Biochemical homology between crystal and spore protein of Bacillus thuringiensis.苏云金芽孢杆菌晶体蛋白与孢子蛋白之间的生化同源性。
J Bacteriol. 1968 Sep;96(3):721-6. doi: 10.1128/jb.96.3.721-726.1968.
3
Immunological homology between crystal and spore protein of Bacillus thuringiensis.苏云金芽孢杆菌晶体蛋白与芽孢蛋白之间的免疫同源性
J Bacteriol. 1968 Sep;96(3):713-20. doi: 10.1128/jb.96.3.713-720.1968.
4
The nature of heat resistant toxin in spores of Clostridium botulinum.
Jpn J Microbiol. 1967 Dec;11(4):384-94. doi: 10.1111/j.1348-0421.1967.tb00362.x.
5
Activation of a toxic component of Clostridium botulinum types C and D by trypsin.胰蛋白酶对肉毒梭菌C型和D型有毒成分的激活作用。
Appl Microbiol. 1972 Jul;24(1):108-13. doi: 10.1128/am.24.1.108-113.1972.
6
Homology between enterotoxin protein and spore structural protein in Clostridium perfringens type A.A型产气荚膜梭菌中肠毒素蛋白与芽孢结构蛋白之间的同源性。
Eur J Biochem. 1973 Nov 15;39(2):393-401. doi: 10.1111/j.1432-1033.1973.tb03137.x.
7
Sporulation and C2 toxin production by Clostridium botulinum type C strains producing no C1 toxin.不产生C1毒素的C型肉毒梭菌菌株的芽孢形成和C2毒素产生
Microbiol Immunol. 1978;22(10):591-6. doi: 10.1111/j.1348-0421.1978.tb00409.x.