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四株卡介苗分枝杆菌疫苗株的霉菌酸模式

Mycolic acid patterns of four vaccine strains of Mycobacterium bovis BCG.

作者信息

Minnikin D E, Minnikin S M, Dobson G, Goodfellow M, Portaels F, van den Breen L, Sesardic D

出版信息

J Gen Microbiol. 1983 Mar;129(3):889-91. doi: 10.1099/00221287-129-3-889.

DOI:10.1099/00221287-129-3-889
PMID:6348209
Abstract

Thin-layer chromatography of methanolysates of four widely used vaccine strains of Mycobacterium bovis BCG showed that only one organism had the expected pattern of mycolic acid methyl esters characteristic of Mycobacterium bovis and Mycobacterium tuberculosis. The remaining three BCG strains lacked methoxy mycolic acid.

摘要

对四种广泛使用的卡介苗牛分枝杆菌疫苗株的甲醇解产物进行薄层层析分析，结果显示只有一种菌株具有牛分枝杆菌和结核分枝杆菌特有的预期模式的分枝菌酸甲酯。其余三种卡介苗菌株缺乏甲氧基分枝菌酸。

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Mycolic acid patterns of four vaccine strains of Mycobacterium bovis BCG.四株卡介苗分枝杆菌疫苗株的霉菌酸模式
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