疟疾中的耐药性：三例病例及文献综述
Drug resistance in malaria: three cases and a review.
作者信息
Isaac-Renton J L, Koon A L, Chan R M, Chow A W, Sacks S L
出版信息
Can Med Assoc J. 1983 Sep 1;129(5):454-7.
Drug resistance has been well documented in two species of malarial parasites. Of greatest concern are the rapid developments in the resistance of Plasmodium falciparum to commonly used therapeutic and chemoprophylactic agents. This species, which is capable of producing life-threatening disease, has shown various levels of resistance in different parts of the world. Also, some strains of the most common species causing relapsing disease, P. vivax, exhibit resistance to primaquine. Three cases of malaria that demonstrate various types of drug resistance are presented in this paper.
疟原虫的耐药性在两种疟原虫中已有充分记载。最令人担忧的是恶性疟原虫对常用治疗药物和化学预防药物的耐药性迅速发展。这种能够引发危及生命疾病的疟原虫在世界不同地区表现出了不同程度的耐药性。此外，导致复发疾病的最常见疟原虫种类间日疟原虫的一些菌株对伯氨喹也表现出耐药性。本文介绍了三例显示出不同类型耐药性的疟疾病例。
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