Insulin-like peptides in the lobster Homarus americanus. II. Insulin-like biological activity.

The in vitro incorporation of [14C]glucose into glycogen in lobster muscle was used to measure insulin-like biological activity. Glycogenesis was significantly increased by the same hepatopancreas eluate which was previously found to have the greatest insulin immunoreactivity. Hemolymph but not gut extract also increased the rate of glycogenesis.