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穿透性角膜移植术后角膜内皮的长期变化。一项镜面显微镜研究。

Long-term changes in corneal endothelium following penetrating keratoplasty. A specular microscopic study.

作者信息

Abbott R L, Fine M, Guillet E

出版信息

Ophthalmology. 1983 Jun;90(6):676-85. doi: 10.1016/s0161-6420(83)34514-0.

DOI:10.1016/s0161-6420(83)34514-0
PMID:6350971
Abstract

One hundred clear corneal grafts with a minimum follow-up of 10 years and average follow-up of 17.4 years were studied with specular microscopy. Central and peripheral graft endothelial cell counts as well as central corneal thickness measurements were done and these were correlated with the following parameters: diagnostic subgroups; donor age; graft age (follow-up time); and the postoperative clinical course. The average central endothelial cell counts for the entire series was 684 cells/mm2. Peripheral cell counts were performed in 78 eyes and averaged 749 cells/mm2. Central corneal thickness was measured in 80 eyes and averaged 0.49 mm. There were no statistically significant differences in central or peripheral cell counts when analyzing donor age, graft age, or postoperative course. When cell counts were examined among the diagnostic subgroups, those in the hereditary stromal dystrophy subgroup had a significantly lower cell density when compared to those in the keratoconus subgroup.

摘要

对100例透明角膜移植术患者进行了研究,这些患者最少随访10年,平均随访17.4年,采用角膜内皮显微镜检查。进行了中央和周边移植角膜内皮细胞计数以及中央角膜厚度测量,并将这些结果与以下参数进行关联:诊断亚组;供体年龄;移植角膜年龄(随访时间);以及术后临床病程。整个系列的平均中央内皮细胞计数为684个细胞/mm²。对78只眼进行了周边细胞计数,平均值为749个细胞/mm²。对80只眼进行了中央角膜厚度测量,平均值为0.49mm。分析供体年龄、移植角膜年龄或术后病程时,中央或周边细胞计数无统计学显著差异。在诊断亚组中检查细胞计数时,遗传性基质营养不良亚组的细胞密度与圆锥角膜亚组相比显著更低。

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Long-term changes in corneal endothelium following penetrating keratoplasty. A specular microscopic study.穿透性角膜移植术后角膜内皮的长期变化。一项镜面显微镜研究。
Ophthalmology. 1983 Jun;90(6):676-85. doi: 10.1016/s0161-6420(83)34514-0.
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