Ruusuvaara P
Acta Ophthalmol (Copenh). 1980 Apr;58(2):267-77. doi: 10.1111/j.1755-3768.1980.tb05720.x.
A specular microscope was used to photograph the cell densities of the central cornea of the graft and the peripheral recipient cornea in a total of 32 human eyes. The follow-up period varied from 8 months to 13 years, with an average of 4.7 years. The mean endothelial cell count in the graft was 997 +/- 356 cells/mm2 and 1410 +/- 584 cells/mm2 in the recipient's peripheral cornea. The mean difference in cell counts between donor and recipient tissues was 413 +/- 718 cells/mm2 (29%). There were great disparities between graft and recipient cell densities. One patient with keratoconus had a graft/recipient differential in cell density of 3 to 1. In four cases the cell density was higher in the graft than in the recipient. Of these grafts, two had been stored in M-K medium and two had been cryopreserved. The great difference in cell density observed between the graft and recipient corneas strongly suggests that little, if any, cell migration occurs between graft and recipient. This suggests that the scar tissue forms a barrier to cell migration between graft and recipient.
使用镜面显微镜对32只人眼的移植物中央角膜和受体周边角膜的细胞密度进行拍照。随访期从8个月到13年不等，平均为4.7年。移植物中的平均内皮细胞计数为997±356个细胞/mm²，受体周边角膜中的平均内皮细胞计数为1410±584个细胞/mm²。供体和受体组织之间的细胞计数平均差异为413±718个细胞/mm²（29%）。移植物和受体的细胞密度存在很大差异。一名圆锥角膜患者的移植物/受体细胞密度差异为3比1。在4例中，移植物中的细胞密度高于受体。在这些移植物中，2个保存在M-K培养基中，2个进行了冷冻保存。移植物和受体角膜之间观察到的细胞密度巨大差异强烈表明，移植物和受体之间几乎没有细胞迁移发生。这表明瘢痕组织形成了移植物和受体之间细胞迁移的屏障。
