高血压疾病中的钙拮抗剂：一种新治疗理念的实验证据
Calcium antagonists in hypertensive disease: experimental evidence for a new therapeutic concept.
作者信息
Kazda S, Garthoff B, Luckhaus G
出版信息
Postgrad Med J. 1983;59 Suppl 2:78-83.
PMID:6351044
Abstract
In animal experiments calcium antagonist drugs decrease peripheral vascular resistance, improve renal sodium excretion and thus, diminishing the volume load, reduce cardiac hypertrophy. In experimental malignant hypertension these drugs preserve tissue integrity by inhibiting the deleterious calcium overload of vessels.
摘要
在动物实验中，钙拮抗剂药物可降低外周血管阻力，改善肾脏钠排泄，从而减少容量负荷，减轻心脏肥大。在实验性恶性高血压中，这些药物通过抑制血管有害的钙超载来维持组织完整性。
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