Wexler M J
Surg Clin North Am. 1983 Aug;63(4):905-14. doi: 10.1016/s0039-6109(16)43091-4.
Portal-systemic shunting of all types has failed to improve long-term survival in patients with bleeding esophageal varices and carries a high morbidity and prohibitive mortality in the emergency setting. Direct esophageal approaches are receiving renewed attention. Sclerotherapy promises to be the simplest, safest, and most effective treatment for acute bleeding. Rebleeding is frequent with this technique unless all the varices are subsequently obliterated. Even then, rebleeding may be a recurring hazard, albeit with reduced frequency and increasing interval. For the nonalcoholic patient with a significant life expectancy or in the young patient with cirrhosis, this can be a significant factor. Simple esophageal resection-transection using stapling devices is a rapidly accomplished, simple, and effective operative approach if combined with coronary vein ligation. This procedure deserves a trial earlier in such patients and in those who are failures of repeated sclerotherapy. Extensive esophagogastric devascularization preserving the paraesophageal veins--the Sugiura procedure--is a more extensive undertaking that is probably unnecessary for most and too dangerous for some. At present, it should be reserved for failures of other techniques. It shows promise of long-term effectiveness if performed safely on only certain patients.
各种类型的门体分流术未能提高食管静脉曲张出血患者的长期生存率,且在急诊情况下具有高发病率和令人望而却步的死亡率。直接的食管治疗方法正重新受到关注。硬化疗法有望成为治疗急性出血最简单、最安全且最有效的方法。除非随后所有静脉曲张均被消除,否则采用这种技术时再出血很常见。即便如此,再出血仍可能是一种反复出现的风险,尽管频率降低且间隔时间延长。对于预期寿命较长的非酒精性患者或年轻的肝硬化患者而言,这可能是一个重要因素。如果结合冠状静脉结扎术,使用吻合器进行简单的食管切除横断术是一种快速完成、简单且有效的手术方法。该手术在这类患者以及那些反复硬化治疗失败的患者中应尽早进行尝试。广泛的食管胃去血管化保留食管旁静脉——即苏吉拉手术——是一项更为广泛的操作,对大多数患者可能不必要,对一些患者则过于危险。目前,它应保留用于其他技术治疗失败的情况。如果仅对特定患者安全实施,它显示出长期有效的前景。