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用于测量纤溶酶原激活剂的固相法和纤维蛋白平板法的比较。

The comparison of solid phase and fibrin plate methods for the measurement of plasminogen activators.

作者信息

Millar W T, Smith J F

出版信息

Thromb Res. 1983 Jun 1;30(5):431-9. doi: 10.1016/0049-3848(83)90177-9.

Abstract

A rapid and highly sensitive solid phase assay was compared with the fibrin plate method for the measurement of urokinase, streptokinase and the plasminogen activators in human euglobulin fractions. The solid phase assay was run using glu - or lys - plasminogen, and significant differences were observed in the activation of the plasminogens by urokinase and streptokinase. Plasminogen activator levels in euglobulin fractions were also measureable. Very good agreement was obtained between the fibrin plate and solid phase methods in all cases.

摘要

将一种快速且高度灵敏的固相分析法与纤维蛋白平板法进行比较,以测定人优球蛋白组分中的尿激酶、链激酶和纤溶酶原激活剂。使用谷氨酸或赖氨酸纤溶酶原进行固相分析,观察到尿激酶和链激酶对纤溶酶原的激活存在显著差异。优球蛋白组分中的纤溶酶原激活剂水平也可测量。在所有情况下,纤维蛋白平板法和固相法之间都获得了非常好的一致性。

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