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破骨细胞和单核细胞在体外具有相似的细胞骨架结构和黏附特性。

Osteoclasts and monocytes have similar cytoskeletal structures and adhesion property in vitro.

作者信息

Zallone A Z, Teti A, Primavera M V, Naldini L, Marchisio P C

出版信息

J Anat. 1983 Aug;137 (Pt 1)(Pt 1):57-70.

PMID:6355036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1171792/
Abstract

The distribution of some cytoskeletal structures (microtubules, microfilaments, intermediate filaments) has been studied by indirect immunofluorescence microscopy and affinity purified antibodies in osteoclasts isolated from medullary bone of laying hens and in hen blood monocytes cultured in vitro. Both cell types show similar patterns of distribution of cytoskeletal structures and this further supports the concept that these cells are closely related. Osteoclasts and monocytes are also similar in their adhesion patterns, because they adhere to fibronectin-free areas and show closely comparable cell-to-substrate interactions when observed with interference reflection microscopy.

摘要

通过间接免疫荧光显微镜和亲和纯化抗体,对从产蛋母鸡骨髓骨中分离出的破骨细胞以及体外培养的母鸡血液单核细胞中的一些细胞骨架结构(微管、微丝、中间丝)分布进行了研究。两种细胞类型均显示出相似的细胞骨架结构分布模式,这进一步支持了这些细胞密切相关的概念。破骨细胞和单核细胞在黏附模式上也相似,因为它们黏附于无纤连蛋白区域,并且在干涉反射显微镜观察下显示出极为相似的细胞与底物相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/53e6ec38d918/janat00205-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/a054758be2c3/janat00205-0063-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/4b9e4955f7e6/janat00205-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/46e9a5cf6b1a/janat00205-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/e9b764c40661/janat00205-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/0076e322b02e/janat00205-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/53e6ec38d918/janat00205-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/a054758be2c3/janat00205-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/1613518d67f1/janat00205-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/4b9e4955f7e6/janat00205-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/46e9a5cf6b1a/janat00205-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/e9b764c40661/janat00205-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/0076e322b02e/janat00205-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a33/1171792/53e6ec38d918/janat00205-0070-a.jpg

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本文引用的文献

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Motion picture and electron microscope studies on the embryonic avian osteoclast.关于鸡胚破骨细胞的电影摄影和电子显微镜研究。
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Formation of cell-to-substrate contacts during fibroblast motility: an interference-reflexion study.成纤维细胞运动过程中细胞与底物接触的形成:干涉反射研究
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Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures.培养的禽类破骨细胞与基质的相互作用是由特定的黏附结构介导的。
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The effects of parathyroid hormone or 1,25-dihydroxyvitamin D3 on monocyte-osteoclast fusion.甲状旁腺激素或1,25 - 二羟维生素D3对单核细胞 - 破骨细胞融合的影响。
Calcif Tissue Int. 1988 May;42(5):302-8. doi: 10.1007/BF02556364.
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Induction of monocyte chemotaxis in devascularized rabbit bone.去血管化兔骨中单核细胞趋化性的诱导
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