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关于来自越南难民的两株间日疟原虫对夜猴和按蚊的感染性观察

Observations on the infectivity of two strains of Plasmodium vivax from Vietnamese refugees to Aotus monkeys and anopheline mosquitoes.

作者信息

Collins W E, Warren M, Skinner J C, Huong A Y, Nguyen-Dinh P

出版信息

J Parasitol. 1983 Aug;69(4):689-95.

PMID:6355429
Abstract

Two strains of Plasmodium vivax (NAM and ONG) were isolated from Vietnamese refugees and established in splenectomized Aotus monkeys from Colombia and Bolivia. Mosquito infections were readily obtained from animals with no prior malarial experience or with a history of infection with P. falciparum only. Those animals with previous infections with P. vivax supported only low parasitemias, and the mosquito infections were minimal. Complete development of the sporogonic cycle was obtained with all species of mosquitoes tested. The most susceptible mosquito was An. dirus. Other mosquitoes readily infected with these strains were An. culicifacies, An. maculatus, An. gambiae, An. stephensi, and the two North American species, An. freeborni and An. quadrimaculatus. Transmission from one monkey to another was obtained via the bites of infected An. dirus, An. stephensi, and An. maculatus mosquitoes.

摘要

从越南难民中分离出两株间日疟原虫(NAM和ONG),并在来自哥伦比亚和玻利维亚的脾切除食蟹猴中建立感染。从未感染过疟疾或仅有恶性疟原虫感染史的动物很容易被蚊子感染。那些曾感染过间日疟原虫的动物仅维持低水平的寄生虫血症,且蚊子感染极少。在所测试的所有蚊种中均获得了孢子生殖周期的完整发育。最易感的蚊子是大劣按蚊。其他容易被这些菌株感染的蚊子有库态按蚊、多斑按蚊、冈比亚按蚊、斯氏按蚊,以及两种北美蚊种,弗里博按蚊和四斑按蚊。通过感染的大劣按蚊、斯氏按蚊和多斑按蚊叮咬可实现从一只猴子到另一只猴子的传播。

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