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[人类白细胞抗原B A位点与银屑病的关联。乌拉圭人群样本分析]

[Association of the HLA B A locus and psoriasis. Analysis of a sample from the Uruguayan population].

作者信息

Paciel J, Vignale R A, Pereira A, Severi J, Rodríguez M, Galbarini E

出版信息

Med Cutan Ibero Lat Am. 1983;11(3):155-8.

PMID:6355691
Abstract

Psoriasis is a skin disease affecting up to a 3% of the world's population. New theories try to explain it as disease provoked by many agents and transmitted by an only gen, where the environmental factors are important. This should be confirmed with the association found with HLA and psoriasis. In this paper we study the HLA association with psoriasis as it has been described in populations of the northern hemisphere, 19 patients with vulgar psoriasis were tested by means of 9 HLA A and 15 HLA B antigens. Postulous, arthropatic and palmo-plantar psoriasis were excluded. We employed the NIH microlymphocytotoxicity test. An association with HLA B13 is shown in accordance to some other reports.

摘要

银屑病是一种影响全球多达3%人口的皮肤病。新理论试图将其解释为由多种因素引发并由单一基因传播的疾病,其中环境因素很重要。这一点应通过与HLA和银屑病之间的关联来证实。在本文中,我们研究了HLA与银屑病的关联,正如在北半球人群中所描述的那样,对19例寻常型银屑病患者进行了9种HLA - A和15种HLA - B抗原的检测。排除了脓疱型、关节病型和掌跖型银屑病。我们采用了美国国立卫生研究院的微量淋巴细胞毒性试验。与其他一些报告一致,显示出与HLA - B13存在关联。

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Med Cutan Ibero Lat Am. 1983;11(3):155-8.
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